Coumarins and derivatives
Medchemexpress LLC Coumarin | 91-64-5 | MFCD00006850 | 146.15 | 1 G
Coumarin is a potent and orally active anti-inflammatory agent. It also shows an antinociceptive effect, and antibacterial, antifungal, and anticancer activity.
- Potent and orally active anti-inflammatory agent
- Shows antinociceptive effect
- Exhibits antibacterial, antifungal, and anticancer activity
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | 10 G
6-Hydroxycoumarin is a coumarin exhibiting diverse biological activities. It is noted for its anti-inflammatory, anti-pyretic, anti-oxidant, and vasodilator properties. This compound also demonstrates anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic, and antitumor activities.
- Demonstrates anti-inflammatory, anti-pyretic, and anti-oxidant activities
- Acts as a vasodilator, anti-amoebic, anti-bacterial, and anti-fungal agent
- Exhibits bacteriostatic and antitumor properties
- Appearance: light yellow to light brown solid
- Molecular formula: C9H6O3
- Molecular weight: 162.14
- Purity: 99.32%
- Melting point: 249-253 °C
- Boiling point: 248.82 °C at 760 mmHg
Sigma Aldrich Fine Chemicals Biosciences Esculin hydrate >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 10G
Esculin hydrate >=98.0% (HPLC) | Purity: >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 10G
Medchemexpress LLC 7-Methylcoumarin | 2445-83-2 | MFCD00006880 | 5 G
7-Methylcoumarin is a coumarin derivative known for its potent hepatoprotective and antioxidant properties. It functions as a mechanism-based inhibitor for CYP2A6, a key enzyme involved in drug metabolism. Studies have shown that it can significantly reduce markers of liver damage, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB), in models of CCl4-induced liver injury. Additionally, it helps to restore total protein (TP) and albumin (TA) levels and prevent oxidative stress. It also exhibits an ability to decrease the mitotic activity of *A. sativum* promeristem.
- Possesses potent hepatoprotective properties
- Acts as a mechanism-based inhibitor for CYP2A6
- Reduces markers of liver damage
- Restores protein and albumin levels in serum
- Prevents oxidative stress
- Decreases mitotic activity
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | MFCD00006856 | 10MM 1ML
4-Hydroxycoumarin | 1076-38-6 | MFCD00006856 | 10MM 1ML
Medchemexpress LLC 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester | 134471-24-2 | MFCD00037568 | ≥95.0% | 5 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. It is a blue fluorescent dye for labeling proteins and nucleic acids.
- Fluorescent dye
- Amine-reactive succinimidyl ester
- Labels proteins and nucleic acids
Medchemexpress LLC 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester | 134471-24-2 | 50 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. It is a blue fluorescent dye used for labeling proteins and nucleic acids.
- Amine-reactive succinimidyl ester
- Blue fluorescent dye
- For labeling proteins
- For labeling nucleic acids
Medchemexpress LLC 4-methoxycoumarin | 20280-81-3 | MFCD00017349 | >99.0% | 176.17 g/mol | C10H8O3 | 25 MG
4-methoxycoumarin is a coumarin derivative reported to show antibacterial activity against R. solanacearum and is supplied for research use in small quantities for analytical and biological testing.
- Shows reported antibacterial activity against R. solanacearum.
- Molecular formula: C10H8O3.
- Molecular weight: 176.17 g/mol.
- CAS number: 20280-81-3.
- Typical pack size: 25 mg; intended for research use.
- Reported purity (supplier): >99%.
Medchemexpress LLC (2,5-dioxopyrrolidin-1-yl) 7-hydroxy-2-oxochromene-3-carboxylate | 134471-24-2 | MFCD00037568 | >96.0% | 303.22 g/mol | C14H9NO7 | 10 MG
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is an N-hydroxysuccinimide (NHS)-activated fluorescent labeling reagent that introduces a 7-hydroxycoumarin fluorophore onto primary amines. Provided as a solid for research use, it is intended for bioconjugation and fluorescence-based assays.
- Reacts with primary amines via NHS ester chemistry for covalent labeling.
- Provides a blue/UV-excitable coumarin fluorophore suitable for protein, peptide, and nucleic acid labeling.
- Available in small-scale quantities convenient for analytical and preparative labeling.
- High chemical purity suitable for coupling reactions (suppliers report >96%).
- Stable when stored as directed; consult the product datasheet or certificate of analysis for storage and handling details.
Medchemexpress LLC 6-Methylcoumarin | 92-48-8 | 160.17 | 1 G
6-Methylcoumarin is a synthetic fragrance widely used in cosmetics. It is reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models and is for research use only. Store powder at -20°C for 3 years or 4°C for 2 years. When in solvent, store at -80°C for 2 years or -20°C for 1 year.
- Purity: 99.98%
- Appearance: Solid
- Color: White to off-white
Cayman Chemical 7-EthoxycoumarIn 500mg
A CYP450 substrate; undergoes O-deethylation by various CYP isoforms; has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea
TARGETMOL CHEMICALS INC HX 531 10MG
Also available in 1 mg 5 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. HX 531 is a potent antagonist of the retinoid X receptor with an IC50 value of 18 nM. purity: 99%
eMolecules 185040-35-1 | 4-Ethylamino-2-methanethiopyrimidine-5-carboxaldehyde | 1g
Ambeed | 4-Fluoro-5-methoxy-1H-indole | 100mg | 561133591 | A355562 | 288385-89-7 | MFCD12924604 | 165.167 | C9H8FNO
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